Keywords
cerebral amyloid
angiopathy-related inflammation
CAA-ri
SARS-CoV-2
radiological image
diagnostic imaging
MRI
angiopathy-related inflammation
CAA-ri
SARS-CoV-2
radiological image
diagnostic imaging
MRI
How to Cite
Dębicka, M. (2021). Cerebral amyloid angiopathy-related inflammation (CAA-ri) in a patient positive for SARS-CoV-2 – radiological findings and differential diagnosis. Wiedza Medyczna, 3(2), 37-40. https://doi.org/10.36553/wm.95
Abstract
84-year old female with confirmed, asymptomatic SARS-CoV-2 infection was admitted to Neurology Department after sudden onset of left-sided hemiparesis and impaired consciousness. Imaging played a key role in diagnostic process, in course of which the diagnosis of cerebral amyloid angiopathy-related inflammation (CAA-ri) was made.
According to latest research, SARS-CoV-2 infection is considered to cause various neurological complications. To my best knowledge this is the first case of CAA-ri and SARS-CoV-2 coexistence to be reported.
References
[1]Chung KK, Anderson NE, Hutchinson D, Synek B, Barber PA. Cerebral amyloid angiopathy related inflammation: three case reports and a review. J Neurol Neurosurg Psychiatry. 2011;82(1):20-26. doi:10.1136/jnnp.2009.204180
[2]Kirshner HS, Bradshaw M. The Inflammatory Form of Cerebral Amyloid Angiopathy or "Cerebral Amyloid Angiopathy-Related Inflammation" (CAARI). Curr Neurol Neurosci Rep. 2015;15(8):54. doi:10.1007/s11910-015-0572-y
[3] Auriel E, Charidimou A, Gurol ME, et al. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016;73(2):197-202. doi:10.1001/jamaneurol.2015.4078
[4] Bag AK, Curé JK, Chapman PR, Roberson GH, Shah R. JC virus infection of the brain. AJNR Am J Neuroradiol. 2010;31(9):1564-1576. doi:10.3174/ajnr.A2035
[5] Anderson RC, Patel V, Sheikh-Bahaei N, et al. Posterior Reversible Encephalopathy Syndrome (PRES): Pathophysiology and Neuro-Imaging. Front Neurol. 2020;11:463. Published 2020 Jun 16. doi:10.3389/fneur.2020.00463
[2]Kirshner HS, Bradshaw M. The Inflammatory Form of Cerebral Amyloid Angiopathy or "Cerebral Amyloid Angiopathy-Related Inflammation" (CAARI). Curr Neurol Neurosci Rep. 2015;15(8):54. doi:10.1007/s11910-015-0572-y
[3] Auriel E, Charidimou A, Gurol ME, et al. Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016;73(2):197-202. doi:10.1001/jamaneurol.2015.4078
[4] Bag AK, Curé JK, Chapman PR, Roberson GH, Shah R. JC virus infection of the brain. AJNR Am J Neuroradiol. 2010;31(9):1564-1576. doi:10.3174/ajnr.A2035
[5] Anderson RC, Patel V, Sheikh-Bahaei N, et al. Posterior Reversible Encephalopathy Syndrome (PRES): Pathophysiology and Neuro-Imaging. Front Neurol. 2020;11:463. Published 2020 Jun 16. doi:10.3389/fneur.2020.00463
This work is licensed under a Creative Commons Attribution 4.0 International License.
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